Gene information
Official symbol CES1
Official full name carboxylesterase 1
Gene type protein-coding gene
Chromosome16q12.2
Alias symbolHMSE; CES2; HMSE1; SES1; CEH; CES1A1; CES1A2
Gene familyCarboxylesterases
Resources
Entrez Gene 1066
HGNC HGNC:1863
Ensembl ENSG00000198848
Vega OTTHUMG00000176718
UCSC uc002eil.4
GO terms: 70 records
GO Description Category LogP Number of genes Detail
GO:0005811 lipid droplet GO Cellular Components -1.49005268 4 More
GO:0006066 alcohol metabolic process GO Biological Processes -16.7128396 29 More
GO:0006631 fatty acid metabolic process GO Biological Processes -20.3287405 33 More
GO:0006694 steroid biosynthetic process GO Biological Processes -2.61471913 6 More
GO:0006695 cholesterol biosynthetic process GO Biological Processes -3.02599739 4 More
GO:0006869 lipid transport GO Biological Processes -16.6388990 29 More
GO:0008202 steroid metabolic process GO Biological Processes -19.3229835 29 More
GO:0008203 cholesterol metabolic process GO Biological Processes -19.4799126 22 More
GO:0008610 lipid biosynthetic process GO Biological Processes -6.38047816 23 More
GO:0009636 response to toxic substance GO Biological Processes -18.1818984 46 More
GO:0010565 regulation of cellular ketone metabolic process GO Biological Processes -15.3155739 32 More
GO:0010874 regulation of cholesterol efflux GO Biological Processes -13.5117096 13 More
GO:0010875 positive regulation of cholesterol efflux GO Biological Processes -12.4669764 10 More
GO:0010876 lipid localization GO Biological Processes -20.1994935 34 More
GO:0010883 regulation of lipid storage GO Biological Processes -22.5241589 19 More
GO:0010885 regulation of cholesterol storage GO Biological Processes -14.3909835 10 More
GO:0010887 negative regulation of cholesterol storage GO Biological Processes -7.00336814 5 More
GO:0010888 negative regulation of lipid storage GO Biological Processes -13.5596033 10 More
GO:0015850 organic hydroxy compound transport GO Biological Processes -17.9399475 23 More
GO:0015918 sterol transport GO Biological Processes -16.3959877 17 More
GO:0016042 lipid catabolic process GO Biological Processes -9.62855375 20 More
GO:0016125 sterol metabolic process GO Biological Processes -19.5624674 23 More
GO:0016126 sterol biosynthetic process GO Biological Processes -2.74134667 4 More
GO:0016298 lipase activity GO Molecular Functions -10.3255371 15 More
GO:0016788 hydrolase activity, acting on ester bonds GO Molecular Functions -4.57583420 56 More
GO:0019216 regulation of lipid metabolic process GO Biological Processes -24.8423986 38 More
GO:0019218 regulation of steroid metabolic process GO Biological Processes -14.2494824 17 More
GO:0030301 cholesterol transport GO Biological Processes -18.3843949 17 More
GO:0030855 epithelial cell differentiation GO Biological Processes -14.2408795 69 More
GO:0032365 intracellular lipid transport GO Biological Processes -4.08159325 5 More
GO:0032366 intracellular sterol transport GO Biological Processes -5.09468573 5 More
GO:0032367 intracellular cholesterol transport GO Biological Processes -5.51573627 5 More
GO:0032368 regulation of lipid transport GO Biological Processes -34.5766289 54 More
GO:0032370 positive regulation of lipid transport GO Biological Processes -15.5410017 17 More
GO:0032371 regulation of sterol transport GO Biological Processes -19.2332049 29 More
GO:0032373 positive regulation of sterol transport GO Biological Processes -13.7255371 12 More
GO:0032374 regulation of cholesterol transport GO Biological Processes -19.2332049 29 More
GO:0032376 positive regulation of cholesterol transport GO Biological Processes -13.7255371 12 More
GO:0032787 monocarboxylic acid metabolic process GO Biological Processes -19.1871601 38 More
GO:0042632 cholesterol homeostasis GO Biological Processes -21.5492593 34 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043691 reverse cholesterol transport GO Biological Processes -17.1886584 11 More
GO:0044070 regulation of anion transport GO Biological Processes -12.6410846 24 More
GO:0044283 small molecule biosynthetic process GO Biological Processes -16.6163676 33 More
GO:0045834 positive regulation of lipid metabolic process GO Biological Processes -24.1838255 28 More
GO:0045940 positive regulation of steroid metabolic process GO Biological Processes -11.4541194 10 More
GO:0046165 alcohol biosynthetic process GO Biological Processes -3.02044097 6 More
GO:0046890 regulation of lipid biosynthetic process GO Biological Processes -16.6841590 23 More
GO:0050810 regulation of steroid biosynthetic process GO Biological Processes -7.92957130 10 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0052689 carboxylic ester hydrolase activity GO Molecular Functions -5.71815649 11 More
GO:0055088 lipid homeostasis GO Biological Processes -20.8046481 43 More
GO:0055092 sterol homeostasis GO Biological Processes -21.3864243 34 More
GO:0055094 response to lipoprotein particle GO Biological Processes -14.9317808 12 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0062013 positive regulation of small molecule metabolic process GO Biological Processes -17.9792910 37 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071402 cellular response to lipoprotein particle stimulus GO Biological Processes -16.0665913 13 More
GO:0071404 cellular response to low-density lipoprotein particle stimulus GO Biological Processes -11.9646006 9 More
GO:0071407 cellular response to organic cyclic compound GO Biological Processes -19.6857751 39 More
GO:0090181 regulation of cholesterol metabolic process GO Biological Processes -6.71495876 7 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0097306 cellular response to alcohol GO Biological Processes -7.74675957 11 More
GO:1901615 organic hydroxy compound metabolic process GO Biological Processes -22.7091625 41 More
GO:1901617 organic hydroxy compound biosynthetic process GO Biological Processes -2.99916656 8 More
GO:1902652 secondary alcohol metabolic process GO Biological Processes -19.9585075 23 More
GO:1902653 secondary alcohol biosynthetic process GO Biological Processes -3.02599739 4 More
GO:1905952 regulation of lipid localization GO Biological Processes -40.6150331 64 More
GO:1905953 negative regulation of lipid localization GO Biological Processes -25.1573575 31 More
GO:1905954 positive regulation of lipid localization GO Biological Processes -22.7388039 24 More
Drug-Gene interaction
view
Related drugs: 11 records
Drug name Interaction type Source PMID View
7-ethyl-10-hydroxycamptothecin PharmGKB view
capecitabine PharmGKB 28139840 view
clopidogrel PharmGKB 23275066274502322570424324535487 view
dabigatran PharmGKB 2346786027261537 view
diacetylmorphine PharmGKB 31837295 view
eldacimibe TTD view
enalapril PharmGKB 25919042 view
irinotecan PharmGKB view
methylphenidate PharmGKB 19733552 view
pactimibe TTD view
trandolapril PharmGKB 19185566 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_001266.5:c.224G>A genomics acute myocardial infarction[diagnosis] acute myocardial infarction Xiao FY et al. Sci Rep. 2017
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